The IIH WT Clinical Trial - IIH Research in the UK

The home of interesting articles and research on IIH and related matters

Moderators: Moderators, Trustees

Forum rules
The General IIH Questions and Answers board is for posting general questions about IIH that don't fit into one of the other specific categories on the forum. If you're not sure where it goes, post it in here, and if a moderator feels it's more appropriate in another board. Below are some points to remember when posting on this board, and also some guidance on what not to post on this board and where it's more appropriate to put it.

General posting guidelines for the board:
  • please post only general IIH related questions in this board - specific questions about particular aspects of IIH should go on the relevant board in the "Discussions section of the site, i.e. 'Medical Treatments', 'Surgical Treatments', etc.
  • please remember that we're not doctors, and shouldn't be giving medical advice - please see the relevant sections in the forum's rules about medical advice and prescription medication. Sharing your experiences of what's worked for you and your IIH is fine, but you shouldn't be telling other members things like, "If you take X, Y and Z it will improve your symptoms" - there's more guidance on this in the forum rules.
  • please start a new thread for each of your questions, which will help other members who are searching for information on a specific subject and allow others to comment on your questions. If you're commenting on another member's post, please don't add in another question of your own to the discussion - start another thread for it.

What shouldn't be posted on this board:
  • news of your latest appointment, your progress following surgery, progress on a new medication etc. should not be posted on this board, but should be posted in the "Members' stories and updates" board
  • if it's a specific question about a particular treatment, please post it in the appropriate board within the "Treatment" section of the forum
  • Introductions should be posted on the "Introductions" board in the "Members' Area" of the forum
  • more general posts about how you're feeling related to IIH should go in the "Need Support?" section of the forum (registered members only in the 'Need Support?' board)
  • this area is for IIH related discussions only - general conversations, jokes etc. should go in the "Members' Area" - general conversations in either the "General Chat" board, or the "Members Lounge" (registered members only in the Members' Lounge)
...and of course as always, play nice and stick to the rules. ;)

Thanks.

This board is for general questions and answers relating to IIH only. Any other posts will be moved into the appropriate board by the forum staff.
Post Reply
iih
Ganglion
Posts: 157
Joined: Fri Feb 17, 2017 9:04 am

The IIH WT Clinical Trial - IIH Research in the UK

Post by iih » Fri Feb 24, 2017 4:44 pm

Treatment of Idiopathic Intracranial Hypertension: the IIH:WT community weight loss programme for the sustained A randomised controlled trial of bariatric surgery versus a community weight loss programme for the sustained treatment of Idiopathic Intracranial Hypertension.

Over 90% of patients with IIH are overweight and weight loss is the most effective treatment. Other treatments for IIH have very little current evidence to support their use. This trial aims to compare two methods of weight loss, bariatric surgery and the most effective dietary programme commonly available, Weight Watchers, to see which offers the most effective longterm treatment for IIH. Bariatric surgery is recommended by the NICE clinical guidelines for patients with a Body Mass Index (BMI) of over 40, or over 35 with a co-morbidity. Women suffering from IIH have a BMI on average around 38 and IIH is not recognised as a co-morbidity for bariatric surgery.

Current therapy for IIH
The 2005 Cochrane review concluded that there was insufficient evidence to determine which treatments were potentially beneficial and which were harmful in IIH (3); hence there are no specific guidelines regarding the treatment of IIH.

Weight loss, achieved through intensive dieting, is an effective therapeutic strategy in IIH. However long-term maintenance of weight loss is notoriously poor, which leads to the recurrence of symptoms: patients in the IIH weight loss study were noted to regain weight and consequently their symptoms and signs of IIH relapsed, a documented phenomenon in the condition. Despite the relapse in IIH following weight gain, our study provides evidence of the efficacy of therapeutic weight loss. Consequently, sustainable approaches to weight loss in IIH are likely to offer patients an effective, potentially curative treatment. We wish to assess if sustained weight loss will result in sustained reduction of ICP, visual symptoms and headaches, and if bariatric surgery is a viable method of achieving this.

Trustees of IIH UK sit as the patient representative on the trial steering committee - please visit the IIH UK website for more information on this trial. In addition to determining if weight loss is an effective treatment for IIH, there are many sub studies being undertaken in this trial, which may well drive future IIH research. http://www.iih.org.uk/research

Post Reply

Who is online

Users browsing this forum: No registered users and 2 guests